COVID Is Alive and Well

I hired a contractor last week to do some work on my house. He and his crew were supposed to start today. This morning I received the following text message from him:

So, folks, if you think COVID is gone and things are returning back to “normal,” you’ve got another think coming. COVID is alive and, well, it’s still fucking us over.

79 thoughts on “COVID Is Alive and Well

  1. Marilyn Armstrong August 10, 2022 / 12:50 pm

    Yes. I’m amazed we haven’t gotten it yet. I actually tested myself this morning. Just in case. Still negative. It may never go away.

    Liked by 1 person

    • Fandango August 10, 2022 / 1:54 pm

      At least it’s not as severe as it was in 2020 for those who contract it.

      Liked by 1 person

      • Marleen August 10, 2022 / 2:21 pm

        I just had sneezing for a couple weeks, sandwiched in the middle time-wise, with a sore throat (very mild but enough to tell me I was actually infected with something) and trailing with a cough (mostly dry)… still getting over it. I went to a large public event shortly before it came on. Almost no one wears masks. I wish I had tested sooner, so I would really know if it was Covid or not. But it was unlike any cold or flu I’ve ever had… I’m pretty sure it was a version of our Covid-19. My experience of Covid-19 in 2020 (in March after going to the same high falutin’ place) was similar in that it was unlike anything I’d had before (with the dry cough, the loss of smell and so on but otherwise ignorable).

        Liked by 1 person

  2. JT Twissel August 10, 2022 / 1:07 pm

    The good thing most people aren’t ending up in hospitals. God help us come flu season. Good luck!

    Liked by 2 people

  3. Nope, Not Pam August 10, 2022 / 1:09 pm

    Running rampant over here, but masks are still optional 🙄

    Liked by 1 person

  4. ganga1996 August 10, 2022 / 1:18 pm

    Yup we had a crew too who had covid and work was postponed a week. Maybe is it becoming an excuse 🤔.

    Liked by 1 person

    • Fandango August 10, 2022 / 1:55 pm

      Maybe, but they don’t get paid if they don’t do the work.

      Liked by 2 people

  5. pensitivity101 August 10, 2022 / 1:24 pm

    We have had seven families go down with it on our estate in as many weeks, so we know it’s far from over. With the holidaymakers coming in their droves, we are keeping as much distance from everyone as we can.

    Liked by 1 person

  6. Marleen August 10, 2022 / 1:41 pm

    I agree with Ganga (above post) that it might be an excuse. How can you argue with that? Nevertheless, it is still here. My oldest son had it in June.

    Liked by 1 person

    • Marleen August 10, 2022 / 2:04 pm

      My third son lives in New Zealand, where they’ve had very little of it. Yet, they gave vaccines to their population. Because of my very unpleasant and unwelcome reaction to my second Pfizer shot, I recommended to that son that he go with the UK spacing between the two shots (he was also getting Pfizer) rather than the US spacing. So, he did space his two shots out more than I had. That went fine. But he had a very unexpected reaction to his first booster (I would have advised him not to get a booster at that time because it was during Omicron and enough data had come out to show the boosters were pointless against that. But he had just gone with the flow and not asked.) He won’t be getting any more boosters. My oldest son was double-boosted and is very healthy as are all my sons (not overweight, not diabetic or any of that).

      Liked by 1 person

      • Marleen August 23, 2022 / 12:53 pm

        I think those tests that come two in a box that is an orange box are nearly worthless. Not completely worthless, as my oldest son tested positive twice during the couple weeks he felt sick (just sort of under the weather) in June. I went and spent some time with him the day he tested negative with one of those.

        It seemed odd to me that he actually had significant congestion in his nose as with a cold. That has not happened to me with covid-19, and I haven’t heard of it with the original or the variants. He might’ve had a regular cold and covid-19 at the same time. Who knows. His nose cleared out while I sat there visiting.

        My recent negative may have been false. The person I live with started feeling like he might be sick, a few days ago. He wasn’t sure if it was allergies or an ordinary sinus infection coming on; has a history of having to deal with both, but is especially unhappy with sinus infections. He felt worse, last night.

        It still wasn’t quite like a sinus infection, to him, though. So he used one of those aforementioned free-upon-request tests. It displayed negative. To be sure about his status — because I’d told him in the last week they are unreliable — he made an appointment with a pharmacy right away (for this morning).

        He tested positive with their, different, test; just a few hours after the one he’d tried at home. Now that I think about it, I commented to him, a week or so ago, that he seemed like he had a cough… a dry one. He brushed it off. Allergies. Whatever. I hadn’t been concerned about myself in that.

        Yet I wonder if I’ll get over my cough now that he has Paxlovid. He’s been volunteering at that high falutin’ place where I contracted covid-19 from a visiting performer (fromNYc) back in mid March of 2020; and probably a variant from a crowd a month ago. He goes there twice per week, every week.

        Liked by 1 person

        • Marleen August 28, 2022 / 9:32 am

          Oh • My • God

          I even got a PCR test, and the answer they gave me was “inconclusive” — perhaps they’d be able to figure it out if I died. They won’t prescribe Paxlovid unless you test positive.

          Liked by 1 person

          • Marleen August 28, 2022 / 12:27 pm

            The website says not to make treatment decisions based solely on rapid test negative results, but that’s exactly what the nurse practitioner was going to do. I don’t even know why the person gave me the rapid test. I had said they have a lot of false negatives, which is why I’d come in. Afterward, when said person was acting like the visit was over, I asked if they had any PCR tests. Said person looked surprised and asked if I wanted one. Given that the individual I live with tested positive and I have symptoms… and the rapid tests have a lot of false negatives… yes.

            By the afternoon, that day, I was completely flattened and sleeping. Then slept through the night as well. And the better part of the next day. Later that next day, I was nauseous and felt I might throw up unless I sat in a certain position (did throw up once when I tried to eat and wasn’t sitting in said position). Plus, the fluid that had been only a runny nose the day before had gotten into my upper lungs. The professional had asked me if I’d had any wheezing when breathing. I hadn’t, then, but now this is where I’d gotten to.

            (And I had other symptoms, both when I went in and then worsening, that I won’t go into so as not to be too boring. I will say this, it is not a dry cough. But the sore throat they speak of now begins as more of a scratch with an annoying near dry and pointless cough, which is different from the actual dry cough [although the same in that the cough was pointless] of the original in 2020 here in the states. If it progresses, the cough is no longer pointless these days.)

            This is, some place(s) on the site called “emergency” symptoms and elsewhere on the site called “moderate” covid (the difference not being the symptoms but whether you choose to go to a hospital which, if you go, then becomes [again in terms of nomemclature] something like extreme covid).


            Key times to get tested:
            If you have symptoms, test immediately.

            If you were exposed to COVID-19 and do not have symptoms, wait at least 5 full days after your exposure before testing. If you test too early, you may be more likely to get an inaccurate result.

            Liked by 1 person

          • Marleen August 28, 2022 / 4:22 pm

            They recommended retesting. I asked the person on the phone how long re-administrating the test might be relevant. I’m thinking of the five day and ten day (and “at least eleven” day) recommendations per isolating or wearing a mask, and I say, “If it’s been three (since the test) days…” The answer delivered was, “I’d give it five days.” I’m not sure what to make of that. (Asking further questions from most people, who seem to not know half of what they’re doing, doesn’t reap meaningful content). If Paxlovid is only to be started within the first five days…

            Or, if all that is important to me is that I want to know what I had…


            Types of Tests

            Viral tests look for a current infection with SARS-CoV-2, the virus that causes COVID-19, by testing specimens from your nose or mouth. There are two main types of viral tests: nucleic acid amplification tests (NAATs) and antigen tests. In certain circumstances, one test type may be recommended over the other. All tests should be performed following FDA’s requirements.

            NAATs, such as PCR-based tests, are most often performed in a laboratory. They are typically the most reliable tests for people with or without symptoms. These tests detect viral genetic material, which may stay in your body for up to 90 days after you test positive. Therefore, you should not use a NAAT if you have tested positive in the last 90 days.

            Antigen tests* are rapid tests which produce results in 15-30 minutes. They are less reliable than NAATs, especially for people who do not have symptoms. A single, negative antigen test result does not rule out infection. To best detect infection, a negative antigen test should be repeated at least 48 hours apart (known as serial testing). Sometimes a follow-up NAAT may be recommended to confirm an antigen test result.

            *Self-tests, or at-home tests… ~

            Liked by 1 person

            • Marleen August 28, 2022 / 5:02 pm

              Viral tests look for a current infection with SARS-CoV-2, the virus that causes COVID-19, by testing specimens from your nose or mouth.

              Notice, “nose or mouth.” My son in New Zealand said that when he got sick (which was, indeed, after being vaccinated and boosted) his home test showed negative when he took the swab sample from the nose, but positive when he took it from his throat. (Apparently the directions there are throat, not mouth.) When the nurse practitioner handed me the swab stick for the PCR test, I asked a question: “Nose or throat?” The professional was again surprised — this time befuddled too — and said, “Only the nose.” I’m going with wrong.

              Liked by 1 person

  7. Marleen August 10, 2022 / 1:47 pm


    Polio in New York – virologist … breaks down
    … nearly a decade ~ July 22 2022

    I found this very informative. It was in year 2000 when
    the United States switched the type of vaccine being used.

    Liked by 1 person

    • Marleen August 21, 2022 / 2:08 am

      TWiV 929: Empathyology with Andy Slavitt 816 views · 4 hours ago


      • Marleen September 17, 2022 / 2:02 am

        Pandemic failures 162K views · 13 hours ago


        • Marleen September 17, 2022 / 2:27 am

          Two days ago, discussion of SARS-CoV-2, the viral
          origins Lancet report, lab leak possibility still open


    • Marleen August 31, 2022 / 1:27 pm

      Posted a bit over five hours ago, recorded two days or so ago, this is even a new topic to the very experienced man who heads up these conversations.

      TWiN [this week in neurolgy] describes how neurotropic viruses leave the brain via meningeal lymphatic vessels located dorsally and basally beneath the skull.

      Liked by 1 person

  8. RuthScribbles August 10, 2022 / 2:04 pm

    my ex died from complications of COVID – just a week ago.

    my grandson (almost 10) had Covid in January and has not really been well since then and just spent a few days in ICU – they still can’t find a reason for what is going on.

    Friends in this area all getting COVID – randomly.

    Liked by 1 person

  9. annieasksyou August 10, 2022 / 3:30 pm

    On our way home from vacation last week, we had lunch at a Panera restaurant. I was uncomfortably close to the woman at the next table. Back on the road, my state’s health dept phone app told me my phone had just been near a phone of someone who had Covid (!). I tested myself three days later: negative, fortunately.

    But I do know others who’ve been infected recently.

    I wear masks a lot.

    Liked by 1 person

  10. Jay August 10, 2022 / 3:34 pm

    It is, and it’s going to get worse, in my opinion. A new conspiracy theory is running here that the covid vaccine will give you the monkey pox. Why? Because “they” (don’t ask who they are) want to kill people to decrease world population.

    With how quickly these things spread, I’m pretty sure it’ll make its way there soon if it hasn’t already!

    Liked by 1 person

    • Marleen August 10, 2022 / 4:19 pm

      😂 Monkeypox (and the sluggish and poor response to it) is bad enough without pretending it comes from the vaccine(s). And monkeypox existed long before Covid-19. The only actual connection reported is that the same lab (in Wuhan) that was doing gain-of-function research on Covid was also doing gain-of-function research on monkeypox. Separately.

      Liked by 2 people

      • Jay August 10, 2022 / 8:54 pm

        Exactly! It drives me batty that people refuse to take a few minutes to do a quick google search and figure out whether or not what they’re saying makings sense! Seems like the general attitude is more around the lines of “well, it might be true, so I’ll share it anyway!”

        Liked by 2 people

          • Jay August 11, 2022 / 5:29 am

            That’s my mother’s logic. She gets stuff from a group of ladies she belongs to and “they wouldn’t share if it wasn’t true!”

            Liked by 1 person

  11. Taswegian1957 August 10, 2022 / 4:16 pm

    It’s a regular thing now, businesses being short handed or closed due to Covid. We have been lucky not to get it and I think it is because we barely socialise and live in an isolated community. I see a lot of people in our town wearing masks as we have a large elderly population but it’s all voluntary now. I have to wear one at my volunteer job but usually I don’t elsewhere because it steams my glasses up.

    Liked by 1 person

  12. Sadje August 10, 2022 / 6:15 pm

    I know that because people are getting it here too. My son and his family have just recovered from it and so has a friend. I got another booster after my surgery and I think though the symptoms aren’t that severe, a booster every 6 months is a good idea.

    Liked by 1 person

  13. lifelessons August 10, 2022 / 8:49 pm

    Just discovered my housesitter who left a week ago and who was headed back here after a trip to other parts of Mexico has Covid. Also, my sister got it while we were traveling together and my last houseguest arrived with it and had to sequester here. So far, I haven’t caught it. Knock Wood.

    Liked by 1 person

    • Fandango August 10, 2022 / 10:04 pm

      It definitely hasn’t disappeared, as some would like us to believe. I hope you don’t contract it, Judy.


      • donmatthewspoetry August 11, 2022 / 3:01 am

        Like many countries we just have to learn to live with it I’m afraid. It won’t just disappear…..

        Liked by 1 person

  14. donmatthewspoetry August 11, 2022 / 2:59 am

    I’m glad to hear your little
    COVID’s still around
    Alive and well it seems (you say)
    Racing leaps and bounds

    Make sure you don’t catch it. Trouble is it’s in the air. And one can never tell…….

    Liked by 1 person

      • Lolsy's Library August 11, 2022 / 11:02 pm

        I’m alright, lol. I appear to have vertigo or something today, and I’m not even sure it is COVID related, lol

        Liked by 1 person

  15. Goin' the extra...aaamile August 13, 2022 / 6:01 am

    oh yes! truly alive. I need to start wearing my mask again. I seem to be taking life way too normal of late. Thanks for the reminder, Fandango. Like always – you’re a savior 🙂

    Liked by 1 person

  16. leigha66 August 14, 2022 / 9:57 pm

    I expect with the return of the school year and the cooling fall coming there will be a big spike late summer early fall… here even the clinic has gone to masks optional though and there are so few people wearing them still. It is not over yet.

    Liked by 1 person

  17. Marleen August 16, 2022 / 11:22 pm

    Thai vaccine study · 17 hours ago

    Liked by 1 person

    • Marleen August 17, 2022 / 2:03 am

      … Vaccine Study | What can we learn? | A Doctor and Professor Reflects

      Liked by 1 person

      • Marleen August 17, 2022 / 10:40 am

        Vaccine Associated Heart Damage in Children

        Liked by 1 person

  18. Marleen August 18, 2022 / 11:22 am

    17 hrs ago | CDC Reorg, SARS-COV-2
    Persistence for Years, and More News

    Liked by 1 person

  19. Marleen August 18, 2022 / 1:02 pm

    Study: Vaccinated 5X More Contagious Than the
    Unvaccinated 10 Days After SARS-coV-2 Infection | 2 h ago

    Liked by 1 person

    • Marleen August 21, 2022 / 2:46 pm

      I’m sharing this information, at this point, because these (the video right above and the — nearly hidden key — content of this link below) are two factoids that I find to be even more sparsely known than the fact kids don’t generally need covid-19 vaccines (and can be harmed by them, especially boys, at high rates).

      The whole article is interesting, and one of the best succinct articles I’ve read. Within it, one can see (if looking closely) that J&J never got approved (despite many news outlets and people in general regularly mixing and matching “approval” (approval in full) and “authorized”/authorization (for emergency distribution) as if the terminologies were/are interchangeable). Actually, a third little-known fact is that requirements for the companies to do follow-up studies is poorly enforced and lax to begin with these days (not so lax when our legacy vaccines were coming out).

      I have an excerpt from about midway through the article beneath the link. My experience is that the piece I put in boldface is false. Johns Hopkins might want it to be true and even think it’s true; it might be the proper way things are supposed to go. However, the vaccines were administered in large group settings rather than doctors’ offices in my area or state (I don’t know about other states). Therefore, I looked closely over all the paperwork the providers carefully made sure everybody received when getting jabs. There was absolutely nothing about reporting adverse effects or injuries. And the topic hardly ever came up in other places; was frequently responded to with shaming as to conspiracy theories when breached. When VAERS occasionally slipped out in news, there was (usually) no care to be clear what had been said, and certainly no contact information. Since people were not e courage’s to contact VAERS, the “data” is unreliable.

      Using Data to Approve COVID-19 Vaccines

      Hundreds of millions of COVID-19 vaccine doses have been given to people in countries all over the world. People who get the vaccines are encouraged to report any problems, including any severe side effects. A cooperative effort between the U.S. Centers for Disease Control and Prevention (CDC) and the FDA, the Vaccine Adverse Event Reporting System (VAERS) collects and analyzes reports from people who received a vaccination and who experienced an adverse event, such as a severe side effect, after getting the shot.

      As a result, we now have even more evidence that the two FDA-approved COVID-19 vaccines are safe for most people who receive them…

      Liked by 1 person

      • Marleen August 21, 2022 / 3:09 pm

        Editing corrections and added fact:

        Correction of my typing/autocorrect:
        … there was (usually) no care to be clear what had been said [such as by showing the spelling and indicating the connection that it was all caps standing for something the federal government is said to be set up to process]. Certainly (usually) no contact information. Since people were not encouraged to contact VAERS, the “data” is unreliable.

        Added fact: Subsequent to the date of the article, a third vaccine brand (one that is not mRNA but is also not J&J) was approved for the U.S.

        Liked by 1 person

      • Marleen August 25, 2022 / 1:22 pm

        More experimenting is likely to be available — or dangled — soon. Again, a “greenlight” from the FDA, authorization or “emergency use authorization” or EUA even with recommendation by the CDC afterward, and being “administered” as well, is not actual approval.

        CNN — Moderna submitted its application to the US Food and Drug Administration for emergency use authorization of its updated Covid-19 vaccine booster for use in people age 18 and older, the company said in a news release on Tuesday.

        The move came one day after Pfizer and BioNTech submitted their application for EUA of their updated Covid-19 booster for people age 12 and older.

        If the FDA authorizes the updated vaccines, they could become available in September. The companies’ updated formulations are bivalent vaccines that combine the original vaccines with ones that target[*] Omicron sublineages BA.4 and BA.5, which currently dominates in the United States.

        Moderna’s shot would be administered as a 50-microgram dose, and Pfizer’s as a 30-microgram dose.

        Moderna said Tuesday a Phase 2/3 clinical trial on these boosters is now underway. The data it submitted to the FDA comes from experiments in mice as well as data from humans using a different booster which was updated to protect against the BA.1[*] strain of Omicron.

        “We have worked closely with the FDA …” said Stephane Bancel, chief executive officer of Moderna.

        Next, the FDA will evaluate the data from Moderna and Pfizer and decide whether to authorize the shots.

        “…” FDA spokesperson Abigail Capobianco said in a statement emailed to CNN … “There are data on many millions of individuals who have received the prototype component as a booster. As for the BA.4[and]5 component, a combination of nonclinical data obtained in mice, data from prior variant vaccines (including those to beta, delta, and omicron BA.1), along with … the mRNA platforms will be used for this decision-making.”

        White House Covid-19 Response Coordinator Dr. Ashish Jha has said … it is ultimately up to the FDA as to when the shot will get the greenlight.

        Dr. Peter Marks, director of the FDA’s Center for Biologics Evaluation and Research, said in an interview with the New York Times on Tuesday that the agency will not convene its independent panel of vaccine experts to seek a recommendation on whether to authorize updated Covid-19 shots.

        Marks told the Times … that he is “extremely confident” … even though the formulations for the updated boosters have not been tested in humans.

        Independent experts who advise the US Centers for Disease Control and Prevention on its vaccine recommendations are expected to discuss updated Covid-19 vaccines during meetings next week. The CDC’s Advisory Committee on Immunization Practices meetings are scheduled for Thursday, September 1, and Friday, September 2.

        The CDC committee typically meets after vaccines have been authorized by the FDA. Shots can be administered only after the CDC recommends them.


        Liked by 1 person

        • Marleen September 1, 2022 / 12:53 pm

          FDA Authorizes Pfizer & Moderna Bivalent Booster | What does it mean? | A doctor explains · 19 hours ago

          Liked by 1 person

          • Marleen September 7, 2022 / 2:31 pm

            Mostly, the applicable word — authorized on an emergency basis) — is employed; approved is accidentally said by the presenter in at least a couple spots (standing in for the companies being given “permission” to inject rather that used technically as legally defined) in this recording (as of early airing if not re-edited). Still, the stated content [if such mistaken verbiage is kept in mind and compensated for in comprehension] reinforces the video I posted on September first (above) and adds additional professional-level thoughts.

            Millions of people are going to receive injections of something newer yet into their bodies based on claimed antibody levels — and no data on hospitalization or death — in eight mice. EUA is going ahead now, while “human trials” are beginning next month. If it wasn’t obvious before that the population is being treated like Guinea pigs, lab rats, or simply revenue excuses, it should be fairly clear by now; I’d say.

            FDA, BA 5 vaccine · Campbell presentation about two hours ago

            Liked by 1 person

          • Marleen September 7, 2022 / 7:45 pm



            The adapted vaccines made by Pfizer/BioNTech and Moderna will be discussed during an extraordinary meeting of the European Medicines Agency (EMA).

            European nations have been keen to rush through … new … jabs … ahead of a feared COVID surge this winter.

            The[se] two so-called “bivalent” vaccines protect against the earlier BA.1 strain of Omicron, as well as the original COVID virus that emerged in China in 2019. They do not however target the newer and more infectious BA.4 and BA.5 types, which have emerged in recent months as the dominant strains worldwide.

            “The aim of the meeting is to conclude the evaluation of the two applications, if possible,” the Amsterdam-based EMA said.

            “We will communicate on the outcomes of the meeting on 1 September.”

            The agency has said it hopes to approve a separate Pfizer vaccine adapted for the BA.4 and BA.5 types “in the fall”.

            The United States authorized its first anti-Omicron vaccines on Wednesday, approving Pfizer and Moderna jabs that were adapted to tackle BA.4 and BA.5.

            Britain authorized the Moderna vaccine for the BA.1 type in mid-August.


            Liked by 1 person

            • Marleen September 23, 2022 / 11:13 am

              It is generally understood, by medical professionals, that standard reporting on medical issues is pretty messed up. Just in the last two paragraphs, here, there are two mistakes (yet they are mistakes the companies are fine to be popularly misunderstood as they’re good for business). I’m “marking” one. The other, I’m not marking, as it’s internal inconsistency can be fairly easily observed.

              The United States authorized its first anti-Omicron vaccines on Wednesday [the last day of August], approving ❌* Pfizer and Moderna jabs that were adapted to tackle BA.4 and BA.5.

              Britain authorized the Moderna vaccine for the BA.1 type in mid-August.

              * They were authorized (on an emergency basis), per EUA — emergency use authorization. They were not approved.

              Liked by 1 person

  20. Island Traveler August 18, 2022 / 7:14 pm

    It is and its normalcy is an everyday morbidity and mortality event that people no longer care to know till it happens to them . Sad, but it is what post pandemic means. Stay safe.

    Liked by 1 person

  21. Marleen August 18, 2022 / 11:02 pm

    Near Infrared Light Reduces Inflammation via TLR4 In Vitro


    • Marleen September 1, 2022 / 12:35 am

      The measuring this video is showing, for
      boosters, drops off rather quickly — even more quickly than for the originating 2-dose series of Modena or Pfizer studies have shown (and more quickly yet with a second booster than the first booster). So, getting a booster is something that appears best done (if done at all) in clear planned tandem with a specific need for a particular date or activity.

      Omicron BA.5 vs. Vaccines and Previous Infection · 1 month ago

      Liked by 1 person

      • Marleen September 1, 2022 / 12:45 am

        Here’s another example of news outlets not seeming to know or care the difference between authorization and approval (which are quite different but do, I acknowledge, both start with the letter a — but it sure can be perplexing to take in a realization that experimental vaccines have been injected into people). I’m pretty sure the Novavax Covid-19 vaccine has been actually approved, but I’m not certain if it was on the below date or later.


        The CDC’s committee of independent advisors voted unanimously to recommend the vaccine for people ages 18 and older after reviewing the shots’ safety and effectiveness during an hourslong public meeting [July 19, 2022]. CDC Director Dr. Rochelle Walensky backed the recommendation later in the evening, the final step in the U.S. authorization process.

        The CDC, in a statement, said the vaccine will be available to the public in the coming weeks. The Biden administration has secured 3.2 million doses of Novavax’s vaccine so far, according to the Health and Human Services Department.

        The CDC’s approval completes a two-year journey for Novavax, one of the early participants in the U.S. race to produce a vaccine to protect against Covid-19. The small Maryland biotech company received $1.8 billion of taxpayer money from Operation Warp Speed, but struggled to get its manufacturing base in place and ultimately fell behind Pfizer and Moderna.

        Novavax’s vaccine will enter the U.S. at a time when more than three-fourths of U.S. adults, 77%, are now fully vaccinated …


        Liked by 1 person

      • Marleen September 3, 2022 / 11:57 am

        Omicron subvariants, BA.1 and BA.2, displaced by BA.5 in many countries


        Partial evasion of BA.1- and BA.2-induced immunity

        Portugal, one of the first countries affected by a BA.5 predominance

        N = 9,307,996

        All Portuguese residents aged
        12 years and older, (National Census 2021)

        Uninfected people in June 1st 2022 was 5, 328, 287,
        (57% of the Portuguese population over 12)
        (PCR tests and rapid antigen tests to diagnose cases)

        Presence of undocumented infections among the “uninfected” group of individuals

        29.2% of infections were not notified
        (based on the seroprevalence of SARS-CoV-2
        anti-N IgG [not based on spike] in the population)

        National coronavirus disease 2019 registry (SINAVE)
        (all reported cases in the country, regardless of clinical presentation)

        To calculate the risk of BA.5 infection after documented infection with past variants, including BA.1 and BA.2

        Times when different variants represented more than 90% of the isolates

        To calculate their infection risk during the period of BA.5 dominance


        Comparator group

        Population that did not have any documented infection before BA.5 dominance (June 1, 2022)


        We found that previous SARS-CoV-2 infection had a protective effect against BA.5 infection

        Protection was maximal for previous infection with BA.1 or BA.2 (not suprising)


        Portugal more than 98% of the study population completed the primary vaccination series before 2022

        [….] Breakthrough infections with the BA.5 subvariant were less likely among persons with a previous SARS-CoV-2 infection history … especially for previous BA.1 or BA.2 infection, than among uninfected persons.

        Liked by 1 person

  22. Marleen August 18, 2022 / 11:34 pm

    This woman’s health insurance is refusing to cover anything because, as stated, the vaccine was experimental (hers was J&J) and Covid-19 wasn’t an emergency. She’s using the money she saved for a house for her health (and as research for an interdisciplinary and open access and translatable book).

    Liked by 1 person

  23. Marleen August 30, 2022 / 4:25 pm

    New advice on covid vaccination in pregnancy
    [from the UK] 18K views · 54 minutes ago

    Liked by 1 person

    • Marleen August 30, 2022 / 4:43 pm

      The FDA granted emergency use authorization (an EUA) for Johnson & Johnson’s coronavirus vaccine. There are *lots* of articles out there about how well the vaccine works, but not nearly as many about *how* it works. It’s an adenoviral-vectored vaccine. What’s that terminology mean?

      An adenovirus is a type of virus that causes some of the illnesses we collectively refer to as “common colds.” Before I started studying science I’d always thought that the “common cold” was an illness caused by a single virus, but there are actually lots of viruses (including several in the coronavirus family) that cause the same symptoms and get lumped together under the term common cold because most people don’t even go to the doctor when they have a cold and, even if they do, doctors don’t usually go around sequencing the snot of every person who comes to them with sniffles. Bottom line, if you have a cold it might be caused by an adenovirus, it might be caused by a (non-SARS-CoV-2) coronavirus, it might be caused by a rhinovirus, etc. So, adenoviruses are one of those types of viruses that can give you the symptoms of a cold. But can it also give you immunity against SARS-CoV-2, the coronavirus that causes the disease COVID-19? It could if you modify it to deliver parts of SARS-CoV-2 (and take away the cold-causing-ness) and this is the idea behind the J & J vaccine as well as the Oxford/AstraZeneca vaccines, although they use different adenoviruses as their genetic delivery vehicles (vectors).



    • Marleen August 30, 2022 / 5:10 pm



      How it works: The Oxford-AstraZeneca vaccine also uses adenoviruses to carry SARS-Cov-2 genes into cells.

      Number of doses required: Two doses, three months apart.

      Effectiveness: Data from large trials released in November found that the vaccine was 62% effective, but there were issues with that study. Another study published Sunday found that the vaccine only offers “minimal protection” against mild to moderate disease caused by the South African coronavirus variant.

      How long it takes to build immunity: People are protected starting 22 days after the first dose, according to preprint data released on Feb. 3. The Oxford-AstraZeneca vaccine was 76% effective 22 days after the first dose, and 82.4% effective after the second.

      Availability: AstraZeneca hasn’t applied for emergency use authorization in the U.S. yet. Britain gave the Oxford-AstraZeneca vaccine emergency use authorization on Dec. 30 [2020], and India also granted emergency use on Jan. 3. South Africa suspended the use of the Oxford-AstraZeneca vaccine Feb. 7, after data suggests it doesn’t work on the country’s variant [Omicron].

      Liked by 1 person

    • Marleen September 2, 2022 / 11:30 am


      There is no known risk associated with giving inactivated, recombinant viral or bacterial vaccines or toxoids during pregnancy or whilst breastfeeding (Kroger et al, 2013).


      Routine questioning about last menstrual period and/or pregnancy testing is not required before offering the vaccine.

      Surveillance of the inadvertent administration of COVID-19 vaccines in early pregnancy is being conducted for the UK by the UK Health Security Agency Immunisation and Vaccine Preventable Diseases Division, to whom such cases should be reported.1 This surveillance is being undertaken to document safety in women who unknowingly receive a vaccine in early pregnancy.…..

      Liked by 1 person

      • Marleen September 22, 2022 / 10:13 am

        Dr. Campbell doesn’t mention the pregnancy vaccination confusion or emergency use authorization(s) in such specific and potentially delicate circumstance as pregnancy in the video, but he looks at the idea we are [or the UK likewise is] more generally going forward still with EUAs (emergency use authorizations) when we’re not in a pandemic (or emergency) any more. He has a bit of a stammer, more pronounced because he’s putting on a submissive air due to YouTube censoring scientific debate and facts. And he leaves some things understated.

        POTUS, Pandemic is over · out on YouTube yesterday

        … the U.S. Food and Drug Administration amended the emergency use authorizations (EUAs) of the Moderna COVID-19 Vaccine,
        and the Pfizer-BioNTech COVID-19 Vaccine, to authorize [on the emergency basis] bivalent formulations, for use as a single booster dose
        Original strain + …

        Biden administration … placed
        an order for 170 million doses


        Liked by 1 person

        • Marleen September 22, 2022 / 10:45 am

          The companies say clinical trials for the BA.4/BA.5 vaccines will begin [in September]; they need clinical data both for full approval of the vaccines—their recent submissions are only for emergency use authorization—and to help develop future updates. Presumably they will measure recipients’ antibody levels, but not the vaccine’s efficacy against infection or severe disease. Such trials are very expensive and were not done for the BA.1 shot either.

          Liked by 1 person

        • Marleen September 22, 2022 / 6:21 pm

          … Human data… only available BA.1 booster

          BA.1 trails did not look for protection against severe disease…

          For the BA.4/BA.5 boosters, the companies have submitted animal data…not released publicly…

          Pfizer presented preliminary findings in eight mice given BA.4/BA.5 vaccines as their third dose… EMA…

          Showed an increased antibody response to all Omicron variants tested: BA.1, BA.2, BA.2.12.1, BA.4, and BA.5.

          ……. June 17, 2022

          Today, the U.S. Food and Drug Administration authorized emergency use [that’s an emergency classification of authorization and not approval] of the Moderna COVID-19 Vaccine and the Pfizer-BioNTech COVID-19 Vaccine, in children down to 6 months of age.

          December 22, 2021… Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for Pfizer’s Paxlovid


          • Marleen September 22, 2022 / 7:30 pm

            I meant to leave that last portion out of the previous comment for putting the information in this one.


            Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for Pfizer’s Paxlovid (nirmatrelvir tablets and ritonavir tablets, co-packaged for oral use) for the treatment of mild-to-moderate coronavirus disease (COVID-19) in adults and pediatric patients (12 years of age and older weighing at least 40 kilograms or about 88 pounds) with positive results of direct SARS-CoV-2 testing, and who are at high risk for progression to severe COVID-19, including hospitalization or death. Paxlovid is available by prescription only and should be initiated as soon as possible after diagnosis of COVID-19 and within five days of symptom onset.

            “Today’s authorization introduces the first treatment for COVID-19 that is in the form of a pill that is taken orally — a major step forward in the fight against this global pandemic,” said Patrizia Cavazzoni, M.D., director of the FDA’s Center for Drug Evaluation and Research. “This authorization provides a new tool to combat COVID-19 at a crucial time in the pandemic as new variants emerge and promises to make antiviral treatment more accessible to patients who are at high risk for progression to severe COVID-19.”

            Paxlovid is not authorized for the pre-exposure or post-exposure prevention of COVID-19 or for initiation of treatment in those requiring hospitalization due to severe or critical COVID-19. Paxlovid is not a substitute for vaccination in individuals for whom COVID-19 vaccination and a booster dose are recommended. The FDA has approved one vaccine and authorized others to prevent COVID-19 and serious clinical outcomes associated with a COVID-19 infection, including hospitalization and death. The FDA urges the public to get vaccinated and receive a booster if eligible. Learn more about FDA-approved or -authorized COVID-19 vaccines.

            Paxlovid consists of nirmatrelvir, which inhibits a SARS-CoV-2 protein to stop the virus from replicating, and ritonavir, which slows down nirmatrelvir’s breakdown to help it remain in the body for a longer period at higher concentrations. Paxlovid is administered as three tablets (two tablets of nirmatrelvir and one tablet of ritonavir) taken together orally twice daily for five days, for a total of 30 tablets. Paxlovid is not authorized for use for longer than five consecutive days.

            The issuance of an EUA is different than an FDA approval. In determining whether to issue an EUA, the FDA evaluates the totality of scientific evidence available and carefully balances any known or potential risks with any known or potential benefits of the product. Based on the FDA’s review of the totality of the scientific evidence available, the agency has determined that it is reasonable to believe that Paxlovid may be effective for the treatment of mild-to-moderate COVID-19 in authorized patients. The agency has also determined that the known and potential benefits of Paxlovid, when used consistent with the terms and conditions of the authorization, outweigh the known and potential risks of the product. There are no adequate, approved and available alternatives to Paxlovid for the treatment of COVID-19.

            The primary data supporting this EUA for Paxlovid are from EPIC-HR, a randomized, double-blind, placebo-controlled clinical trial studying Paxlovid for the treatment of non-hospitalized symptomatic adults with a laboratory confirmed diagnosis of SARS-CoV-2 infection. Patients were adults 18 years of age and older with a prespecified risk factor for progression to severe disease or were 60 years and older regardless of prespecified chronic medical conditions. *All patients had not received a COVID-19 vaccine and had not been previously infected with COVID-19.* The main outcome measured in the trial was the proportion of people who were hospitalized due to COVID-19 or died due to any cause during 28 days of follow-up. Paxlovid significantly reduced the proportion of people with COVID-19 related hospitalization or death from any cause by 88% compared to placebo among patients treated within five days of symptom onset and who did not receive COVID-19 therapeutic monoclonal antibody treatment. In this analysis, 1,039 patients had received Paxlovid, and 1,046 patients had received placebo and among these patients, 0.8% who received Paxlovid were hospitalized or died during 28 days of follow-up compared to 6% of the patients who received placebo. The safety and effectiveness of Paxlovid for the treatment of COVID-19 continue to be evaluated.

            Possible side effects of Paxlovid include impaired sense of taste, diarrhea, high blood pressure and muscle aches. Using Paxlovid at the same time as certain other drugs may result in potentially significant drug interactions. Using Paxlovid in people with uncontrolled or undiagnosed HIV-1 infection may lead to HIV-1 drug resistance. Ritonavir may cause liver damage, so caution should be exercised when giving Paxlovid to patients with preexisting liver diseases, liver enzyme abnormalities or liver inflammation.

            Because Paxlovid works, in part, by inhibiting a group of enzymes that break down certain drugs, Paxlovid is contraindicated with certain drugs that are highly dependent on those enzymes for metabolism and for which elevated concentrations of certain drugs are associated with serious and/or life-threatening reactions. Paxlovid is also contraindicated with drugs that, conversely, strongly induce those same enzymes, leading to the faster breakdown of nirmatrelvir or ritonavir, as reduced concentrations of nirmatrelvir or ritonavir may be associated with potentially losing virologic response and developing viral resistance. Paxlovid cannot be started immediately after discontinuing such medications because the effects of those medications remain after discontinuation. For a complete list of drugs that should not be taken in combination with Paxlovid, see the fact sheet for healthcare providers.

            Paxlovid is not recommended in patients with severe kidney or severe liver impairment. In patients with moderate renal impairment, a reduced Paxlovid dose is needed. Patients with kidney or liver problems should discuss with their healthcare provider whether Paxlovid is right for them.

            Under the EUA, fact sheets that provide important information about using Paxlovid in the treatment of COVID-19 as authorized must be made available to healthcare providers and to patients and caregivers. These fact sheets include dosing instructions, potential side effects, drug interactions and information about who is able to prescribe Paxlovid.

            Related Information

            Paxlovid EUA Letter of Authorization
            Frequently Asked Questions on the Emergency Use Authorization for Paxlovid
            Emergency Use Authorization: Drugs and Non-Vaccine Biological Products
            Coronavirus Disease (COVID-19)
            Coronavirus Treatment
            Acceleration Program (CTAP)


            {I added the two — *[…]* — asterisks for emphasis in the sixth paragraph, while the boldface of the second paragraph is how the site page appeared, itself. (Accessed within the last hour.)}


  24. Marleen August 30, 2022 / 5:45 pm

    BTW: I don’t know which places ever got around to full approval of Oxford-AstraZeneca — pretty sure the UK did while the US never authorized the counterpart over here, J&J (because of safety reasons rather than efficacy).

    h…s://[3ws].nytimes[dot]com › article › omicron-coronavirus-variant.html

    What We Know About Omicron, BA.4 and BA.5 …
    Jun 14, 2022

    The earliest evidence for Omicron’s swift spread came from South Africa, where Omicron rapidly grew to dominance in one province after another.

    [They discovered/isolated it there in South Africa (and informed the world; didn’t cause it and are not necessarily the only place it existed at the time).]

    Liked by 1 person

    • Marleen September 2, 2022 / 12:28 pm

      Well, dern it! I made the mistake myself, above — while the U.S. hasn’t approved J&J, apparatchiks did authorize it (lower level go-ahead still only experimental). As such, I see it as unethical that this government website doesn’t state clearly which (three) of the vaccines are actually approved. Even if the approved ones aren’t being administered in consistently safer ways than the J&J, insurance companies tend to react differently to your situation.

      There are four approved or authorized vaccines in the United States used to prevent COVID-19. Pfizer-BioNTech and Moderna are COVID-19 mRNA vaccines. You can also get the Novavax COVID-19 protein subunit vaccine. Otherwise, you may get Johnson & Johnson’s Janssen (J&J/Janssen) COVID-19 viral vector vaccine in some situations.

      These vaccines are given as a shot in the muscle of the upper arm or in the thigh.

      Liked by 1 person

      • Marleen September 2, 2022 / 1:50 pm

        In January 2020, just as the pandemic started to take hold, J&J obtained the novel coronavirus’s sequence information from China and validated it.

        From there, the company worked closely with Dr Dan Barouch and his team at the Center for Virology and Vaccine Research at the Beth Israel Deaconess Medical Center, an affiliate of Harvard Medical School, to design a large number of potential candidates for the vaccine. The company had previously collaborated with Barouch on preclinical work for its Zika and HIV vaccine candidates.

        “Due to our extensive previous experience with vaccine technology – we used the same technology to create our European Commission-approved Ebola vaccine – scientists already had a good sense of the best doses to use for the investigational Covid-19 candidate,” said J&J global head of Janssen research & development Dr Mathai Mammen.


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